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Mitochondrial DNA mutations in iPS cells: mtDNA integrity as standard iPSC selection criteria?
Somatic cells harbor random heteroplasmic mitochondrial DNA mutations, which are considered to contribute to aging. In this issue of The EMBO Journal, Perales‐Clemente et al (2016) show that mtDNA mutations, present at low levels in the starting fibroblasts, become enriched in iPS cells and lead to...
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| Publicado no: | EMBO J |
|---|---|
| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282832/ https://ncbi.nlm.nih.gov/pubmed/27469999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695185 |
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