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Mitochondrial Disease: mtDNA and Protein Segregation Mysteries in iPSCs
Mitochondrial diseases cause a range of clinical manifestations even in patients carrying the same mtDNA mutations. New work reveals that a common disease-associated mtDNA mutation is selectively segregated from wild-type mtDNA during the reprogramming of induced pluripotent stem cells and that high...
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| Vydáno v: | Curr Biol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746723/ https://ncbi.nlm.nih.gov/pubmed/24309284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.10.048 |
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