Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis

Eukaryotic translation initiation factor 5A (eIF5A) is a protein that is highly conserved and essential for cell viability. This factor is the only protein known to contain the unique and essential amino acid residue hypusine. This work focused on the structural and functional characterization of Sa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS J
Main Authors: Dias, Camila A. O., Cano, Veridiana S. P., Rangel, Suzana M., Apponi, Luciano H., Frigieri, Mariana C., Muniz, João R. C., Garcia, Wanius, Park, Myung H., Garratt, Richard C., Zanelli, Cleslei F., Valentini, Sandro R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278519/
https://ncbi.nlm.nih.gov/pubmed/18341589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06345.x
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