Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis

Eukaryotic translation initiation factor 5A (eIF5A) is a protein that is highly conserved and essential for cell viability. This factor is the only protein known to contain the unique and essential amino acid residue hypusine. This work focused on the structural and functional characterization of Sa...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Dias, Camila A. O., Cano, Veridiana S. P., Rangel, Suzana M., Apponi, Luciano H., Frigieri, Mariana C., Muniz, João R. C., Garcia, Wanius, Park, Myung H., Garratt, Richard C., Zanelli, Cleslei F., Valentini, Sandro R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278519/
https://ncbi.nlm.nih.gov/pubmed/18341589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06345.x
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