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The Minimal Promoter Region of the Dense Core Vesicle Protein IA-2: Transcriptional Regulation by CREB

IA-2 is a transmembrane protein found in the dense core vesicles (DCV) of neuroendocrine cells and one of the major autoantigens in type 1 diabetes. DCV are involved in the secretion of hormones (e.g., insulin) and neurotransmitters. Stimulation of pancreatic β cells with glucose upregulates the exp...

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Publicat a:Acta Diabetol
Autors principals: Cai, Tao, Hirai, Hiroki, Xu, Huanyu, Notkins, Abner L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5273861/
https://ncbi.nlm.nih.gov/pubmed/25528004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00592-014-0689-5
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