Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2

It is generally accepted that neuroendocrine cells regulate dense core vesicle (DCV) biogenesis and cargo packaging in response to secretory demands, although the molecular mechanisms of this process are poorly understood. One factor that has previously been implicated in DCV regulation is IA-2, a c...

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Main Authors: Cai, Tao, Hirai, Hiroki, Fukushige, Tetsunari, Yu, Ping, Zhang, Guofeng, Notkins, Abner L., Krause, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657203/
https://ncbi.nlm.nih.gov/pubmed/19343207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000447
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