Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans

IA-2 (insulinoma-associated protein 2), a major autoantigen in type 1 diabetes, is a receptor-tyrosine phosphatase-like protein associated with the membrane of secretory granules of neural and endocrine-specific cells. Loss of IA-2 activity in the mouse results in reduced insulin release and additio...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Cai, Tao, Fukushige, Tetsunari, Notkins, Abner L., Krause, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2004
Schlagworte:
Cellular/Molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729843/
https://ncbi.nlm.nih.gov/pubmed/15044551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0101-04.2004
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