טוען...

The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion

IA-2 is an enzymatically inactive member of the transmembrane protein tyrosine phosphate family located in dense core secretory vesicles and a major autoantigen in type 1 diabetes. Recent studies showed that targeted disruption of the IA-2 gene in mice resulted in impairment of insulin secretion and...

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מידע ביבליוגרפי
Main Authors: Harashima, Shin-ichi, Clark, Anne, Christie, Michael R., Notkins, Abner Louis
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150807/
https://ncbi.nlm.nih.gov/pubmed/15939893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408887102
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