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The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion
IA-2 is an enzymatically inactive member of the transmembrane protein tyrosine phosphate family located in dense core secretory vesicles and a major autoantigen in type 1 diabetes. Recent studies showed that targeted disruption of the IA-2 gene in mice resulted in impairment of insulin secretion and...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150807/ https://ncbi.nlm.nih.gov/pubmed/15939893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408887102 |
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