The Dense Core Vesicle Protein IA-2, but not IA-2β, is Required for Active Avoidance Learning

The islet-antigens IA-2 and IA-2β are major autoantigens in type-1 diabetes and transmembrane proteins in dense core vesicles (DCV). Recently we showed that deletion of both IA-2 and IA-2β alters the secretion of hormones and neurotransmitters and impairs behavior and learning. The present study was...

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Hlavní autoři: Carmona, Gilberto Nepthali, Nishimura, Takuya, Schindler, Charles Weber, Panlilio, Leigh Vincent, Notkins, Abner Louis
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038122/
https://ncbi.nlm.nih.gov/pubmed/24662847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.03.023
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