MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis

Atherothrombotic vascular disease is often triggered by a distinct type of atherosclerotic lesion that displays features of impaired inflammation resolution, notably a necrotic core and thinning of a protective fibrous cap that overlies the core. A key cause of plaque necrosis is defective clearance...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cai, Bishuang, Thorp, Edward B., Doran, Amanda C., Sansbury, Brian E., Daemen, Mat J.A.P., Dorweiler, Bernhard, Spite, Matthew, Fredman, Gabrielle, Tabas, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272169/
https://ncbi.nlm.nih.gov/pubmed/28067670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90520
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