The G(S) Protein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center

T follicular helper (T(FH)) cells have been shown to be critically required for the germinal center (GC) reaction where B cells undergo class switch recombination and clonal selection to generate high affinity neutralizing antibodies. However, detailed knowledge of the physiological cues within the...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Abbott, Robert K., Silva, Murillo, Labuda, Jasmine, Thayer, Molly, Cain, Derek W., Philbrook, Phaethon, Sethumadhavan, Shalini, Hatfield, Stephen, Ohta, Akio, Sitkovsky, Michail
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Accelerated Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270467/
https://ncbi.nlm.nih.gov/pubmed/27974461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C116.764043
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