Načítá se...
Distinct Brca1 mutations differentially reduce hematopoietic stem cell function
BRCA1 is a well-known DNA repair pathway component and a tissue-specific tumor suppressor. However, its role in hematopoiesis is uncertain. Here we report that a cohort of patients heterozygous for BRCA1 mutations experienced more hematopoietic toxicity from chemotherapy than those with BRCA2 mutati...
Uloženo v:
| Vydáno v: | Cell Rep |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5267932/ https://ncbi.nlm.nih.gov/pubmed/28122244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.075 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|