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SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors

Hematopoietic stem cells (HSCs) and multipotent hematopoietic progenitors (MPPs) are routinely isolated using various markers but remain heterogeneous. Here we show that four SLAM family markers, CD150, CD48, CD229, and CD244, can distinguish HSCs and MPPs from restricted progenitors and subdivide t...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Oguro, Hideyuki, Ding, Lei, Morrison, Sean J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736853/
https://ncbi.nlm.nih.gov/pubmed/23827712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.05.014
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