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SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors

Hematopoietic stem cells (HSCs) and multipotent hematopoietic progenitors (MPPs) are routinely isolated using various markers but remain heterogeneous. Here we show that four SLAM family markers, CD150, CD48, CD229, and CD244, can distinguish HSCs and MPPs from restricted progenitors and subdivide t...

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Hlavní autoři: Oguro, Hideyuki, Ding, Lei, Morrison, Sean J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736853/
https://ncbi.nlm.nih.gov/pubmed/23827712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.05.014
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