Deficiency of the Endocytic Protein Hip1 Leads to Decreased Gdpd3 Expression, Low Phosphocholine, and Kypholordosis

Deficiency of huntingtin-interacting protein 1 (Hip1) results in degenerative phenotypes. Here we generated a Hip1 deficiency allele where a floxed transcriptional stop cassette and a human HIP1 cDNA were knocked into intron 1 of the mouse Hip1 locus. CMV-Cre-mediated germ line excision of the stop...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Wijayatunge, Ranjula, Holmstrom, Sam R., Foley, Samantha B., Mgbemena, Victoria E., Bhargava, Varsha, Perez, Gerardo Lopez, McCrum, Kelly, Ross, Theodora S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234285/
https://ncbi.nlm.nih.gov/pubmed/30224518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00385-18
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