Caricamento...
Distinct Brca1 mutations differentially reduce hematopoietic stem cell function
BRCA1 is a well-known DNA repair pathway component and a tissue-specific tumor suppressor. However, its role in hematopoiesis is uncertain. Here we report that a cohort of patients heterozygous for BRCA1 mutations experienced more hematopoietic toxicity from chemotherapy than those with BRCA2 mutati...
Salvato in:
| Pubblicato in: | Cell Rep |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5267932/ https://ncbi.nlm.nih.gov/pubmed/28122244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.075 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|