Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation

BACKGROUND: HIV-1 replication is critically dependent upon controlled processing of its RNA and the activities provided by its encoded regulatory factors Tat and Rev. A screen of small molecule modulators of RNA processing identified several which inhibited virus gene expression, affecting both rela...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Balachandran, Ahalya, Wong, Raymond, Stoilov, Peter, Pan, Sandy, Blencowe, Benjamin, Cheung, Peter, Harrigan, P. Richard, Cochrane, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267425/
https://ncbi.nlm.nih.gov/pubmed/28122580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0330-0
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