Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation

BACKGROUND: HIV-1 replication is critically dependent upon controlled processing of its RNA and the activities provided by its encoded regulatory factors Tat and Rev. A screen of small molecule modulators of RNA processing identified several which inhibited virus gene expression, affecting both rela...

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Vydáno v:Retrovirology
Hlavní autoři: Balachandran, Ahalya, Wong, Raymond, Stoilov, Peter, Pan, Sandy, Blencowe, Benjamin, Cheung, Peter, Harrigan, P. Richard, Cochrane, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267425/
https://ncbi.nlm.nih.gov/pubmed/28122580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0330-0
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