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Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function

Expression of the complete HIV-1 genome depends on the appropriate processing of viral RNA. Altering the balance of viral RNA processing impairs replication of the virus. In this report, we characterize two small molecule modulators of HIV-1 RNA processing, 8-azaguanine and 2-(2-(5-nitro-2-thienyl)v...

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Detalhes bibliográficos
Main Authors: Wong, Raymond W., Balachandran, Ahalya, Haaland, Matthew, Stoilov, Peter, Cochrane, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814367/
https://ncbi.nlm.nih.gov/pubmed/23945945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt727
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