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Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing
To develop new approaches to control HIV-1 replication, we examined the capacity of recently described small molecular modulators of RNA splicing for their effects on viral RNA metabolism. Of the drugs tested, digoxin was found to induce a dramatic inhibition of HIV-1 structural protein synthesis, a...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610647/ https://ncbi.nlm.nih.gov/pubmed/23555254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003241 |
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