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Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing

To develop new approaches to control HIV-1 replication, we examined the capacity of recently described small molecular modulators of RNA splicing for their effects on viral RNA metabolism. Of the drugs tested, digoxin was found to induce a dramatic inhibition of HIV-1 structural protein synthesis, a...

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Bibliografske podrobnosti
Main Authors: Wong, Raymond W., Balachandran, Ahalya, Ostrowski, Mario A., Cochrane, Alan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610647/
https://ncbi.nlm.nih.gov/pubmed/23555254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003241
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