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Integrating the Escalation and Dose Expansion Studies into a Unified Phase I Clinical Trial
We focus on Phase I dose finding studies as they are currently undertaken. The design and analysis of these trials has changed over the last years and, in particular, it is now rare for a Phase I study to not include one or more dose- expansion cohorts (DEC). It is common to see DEC involving severa...
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| Publicado no: | Contemp Clin Trials |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5266504/ https://ncbi.nlm.nih.gov/pubmed/27393122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.06.010 |
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