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SHP-1: the next checkpoint target for cancer immunotherapy?
The immense power of the immune system is harnessed in healthy individuals by a range of negative regulatory signals and checkpoints. Manipulating these checkpoints through inhibition has resulted in striking immune-mediated clearance of otherwise untreatable tumours and metastases; unfortunately, n...
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| Published in: | Biochem Soc Trans |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5264497/ https://ncbi.nlm.nih.gov/pubmed/27068940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150251 |
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