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Targeting cancer using KAT inhibitors to mimic lethal knockouts
Two opposing enzyme classes regulate fundamental elements of genome maintenance, gene regulation and metabolism, either through addition of an acetyl moiety by histone acetyltransferases (HATs) or its removal by histone de-acetyltransferases (HDAC), and are exciting targets for drug development. Imp...
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| Опубликовано в: : | Biochem Soc Trans |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Portland Press Ltd.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4984449/ https://ncbi.nlm.nih.gov/pubmed/27528742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160081 |
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