Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells

Increased breast density attributed to collagen I deposition is associated with a 4–6 fold increased risk of developing breast cancer. Here, we assessed cellular metabolic reprogramming of mammary carcinoma cells in response to increased collagen matrix density using an in vitro 3D model. Our initia...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Morris, Brett A., Burkel, Brian, Ponik, Suzanne M., Fan, Jing, Condeelis, John S., Aguire-Ghiso, Julio A., Castracane, James, Denu, John M., Keely, Patricia J.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264313/
https://ncbi.nlm.nih.gov/pubmed/27743905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.10.012
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