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Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro

Rictor is a key regulatory/structural subunit of the mammalian target of rapamycin complex 2 (mTORC2) and is required for phosphorylation of Akt at serine 473. It plays an important role in cell survival, actin cytoskeleton organization and other processes in embryogenesis. However, the role of Rict...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Zheng, Bei, Wang, Jiadan, Tang, Leilei, Tan, Chao, Zhao, Zhe, Xiao, Yi, Ge, Renshan, Zhu, Danyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264266/
https://ncbi.nlm.nih.gov/pubmed/28123351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.16312
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