Yüklüyor......
Deciphering the Fringe-mediated Notch Code: Identification of activating and inhibiting sites allowing discrimination between ligands
Fringe proteins are β3-N-acetylglucosaminyltransferases that modulate Notch activity by modifying O-fucose residues on Epidermal Growth Factor-like (EGF) repeats of Notch. Mammals have three Fringes: Lunatic, Manic, and Radical. While Lunatic and Manic Fringe inhibit Notch1 activation from Jagged1 a...
Kaydedildi:
| Yayımlandı: | Dev Cell |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5263050/ https://ncbi.nlm.nih.gov/pubmed/28089369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.12.013 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|