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CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency

The mechanisms of how signaling pathways are coordinated and integrated for the maintenance of the self-renewal of human embryonic stem cells (hESCs) and the acquisition of pluripotency in reprogramming are still only partly understood. CDK1 is a key regulator of mitosis. Recently, CDK1 has been sho...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wang, Xiao Qi, Lo, Chung Mau, Chen, Lin, Ngan, Elly S-W, Xu, Aimin, Poon, Randy YC
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260505/
https://ncbi.nlm.nih.gov/pubmed/27636107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.84
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