UFM1 suppresses invasive activities of gastric cancer cells by attenuating the expression of PDK1 through PI3K/AKT signaling

BACKGROUND: UFM1 has been found to be involved in the regulation of tumor development. This study aims to clarify the role and potential molecular mechanisms of UFM1 in the invasion and metastasis of gastric cancer. METHODS: Expression of UFM1 in gastric tumor and paired adjacent noncancerous tissue...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Lin, Jian-Xian, Xie, Xin-Sheng, Weng, Xiong-Feng, Qiu, Sheng-Liang, Yoon, Changhwan, Lian, Ning-Zi, Xie, Jian-Wei, Wang, Jia-Bin, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Yang, Ying-Hong, Huang, Chang-Ming, Zheng, Chao-Hui, Li, Ping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751655/
https://ncbi.nlm.nih.gov/pubmed/31533855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1416-4
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