UFM1 suppresses invasive activities of gastric cancer cells by attenuating the expression of PDK1 through PI3K/AKT signaling

BACKGROUND: UFM1 has been found to be involved in the regulation of tumor development. This study aims to clarify the role and potential molecular mechanisms of UFM1 in the invasion and metastasis of gastric cancer. METHODS: Expression of UFM1 in gastric tumor and paired adjacent noncancerous tissue...

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Detaylı Bibliyografya
Yayımlandı:J Exp Clin Cancer Res
Asıl Yazarlar: Lin, Jian-Xian, Xie, Xin-Sheng, Weng, Xiong-Feng, Qiu, Sheng-Liang, Yoon, Changhwan, Lian, Ning-Zi, Xie, Jian-Wei, Wang, Jia-Bin, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Yang, Ying-Hong, Huang, Chang-Ming, Zheng, Chao-Hui, Li, Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751655/
https://ncbi.nlm.nih.gov/pubmed/31533855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1416-4
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