UFM1 suppresses invasive activities of gastric cancer cells by attenuating the expression of PDK1 through PI3K/AKT signaling

BACKGROUND: UFM1 has been found to be involved in the regulation of tumor development. This study aims to clarify the role and potential molecular mechanisms of UFM1 in the invasion and metastasis of gastric cancer. METHODS: Expression of UFM1 in gastric tumor and paired adjacent noncancerous tissue...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Lin, Jian-Xian, Xie, Xin-Sheng, Weng, Xiong-Feng, Qiu, Sheng-Liang, Yoon, Changhwan, Lian, Ning-Zi, Xie, Jian-Wei, Wang, Jia-Bin, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Yang, Ying-Hong, Huang, Chang-Ming, Zheng, Chao-Hui, Li, Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751655/
https://ncbi.nlm.nih.gov/pubmed/31533855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1416-4
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