CDK5RAP3 inhibits angiogenesis in gastric neuroendocrine carcinoma by modulating AKT/HIF-1α/VEGFA signaling

BACKGROUND: Angiogenesis plays critical roles in the progression and metastasis of malignant tumors. Gastric neuroendocrine carcinoma is an uncommon stomach cancer that is rich in blood vessels and exhibits highly malignant biological behavior with a poor prognosis. The role of CDK5RAP3 in GNEC has...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Lin, Jian-Xian, Weng, Xiong-Feng, Xie, Xin-Sheng, Lian, Ning-Zi, Qiu, Sheng-Liang, Wang, Jia-Bin, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Yang, Ying-Hong, Liu, Si-Jia, Hu, Min, Lin, Yi-Ke, Huang, Chang-Ming, Zheng, Chao-Hui, Li, Ping, Xie, Jian-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839262/
https://ncbi.nlm.nih.gov/pubmed/31728130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0997-5
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