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PDK1 regulates growth through Akt and S6K in Drosophila

The insulin/insulin-like growth factor-1 signaling pathway promotes growth in invertebrates and vertebrates by increasing the levels of phosphatidylinositol 3,4,5-triphosphate through the activation of p110 phosphatidylinositol 3-kinase. Two key effectors of this pathway are the phosphoinositide-dep...

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Detalles Bibliográficos
Main Authors: Rintelen, Felix, Stocker, Hugo, Thomas, George, Hafen, Ernst
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC64976/
https://ncbi.nlm.nih.gov/pubmed/11752451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.011318098
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