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Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography

Nephrin is a key functional component of the slit diaphragm, the structurally unresolved molecular filter in renal glomerular capillaries. Abnormal nephrin or its absence results in severe proteinuria and loss of the slit diaphragm. The diaphragm is a thin extracellular membrane spanning the approxi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wartiovaara, Jorma, Öfverstedt, Lars-Göran, Khoshnoodi, Jamshid, Zhang, Jingjing, Mäkelä, Eetu, Sandin, Sara, Ruotsalainen, Vesa, Cheng, R. Holland, Jalanko, Hannu, Skoglund, Ulf, Tryggvason, Karl
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC525744/
https://ncbi.nlm.nih.gov/pubmed/15545998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422562
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