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Role of Nephrin in Cell Junction Formation in Human Nephrogenesis

Nephrin is a cell adhesion protein located at the slit diaphragm area of glomerular podocytes. Mutations in nephrin-coding gene (NPHS1) cause congenital nephrotic syndrome (NPHS1). We studied the developmental expression of nephrin, ZO-1 and P-cadherin in normal fetal kidneys and in NPHS1 kidneys. W...

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Detalhes bibliográficos
Main Authors: Ruotsalainen, Vesa, Patrakka, Jaakko, Tissari, Päivi, Reponen, Paula, Hess, Michael, Kestilä, Marjo, Holmberg, Christer, Salonen, Riitta, Heikinheimo, Markku, Wartiovaara, Jorma, Tryggvason, Karl, Jalanko, Hannu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885750/
https://ncbi.nlm.nih.gov/pubmed/11106563
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