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Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography
Nephrin is a key functional component of the slit diaphragm, the structurally unresolved molecular filter in renal glomerular capillaries. Abnormal nephrin or its absence results in severe proteinuria and loss of the slit diaphragm. The diaphragm is a thin extracellular membrane spanning the approxi...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525744/ https://ncbi.nlm.nih.gov/pubmed/15545998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422562 |
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