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Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography

Nephrin is a key functional component of the slit diaphragm, the structurally unresolved molecular filter in renal glomerular capillaries. Abnormal nephrin or its absence results in severe proteinuria and loss of the slit diaphragm. The diaphragm is a thin extracellular membrane spanning the approxi...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Wartiovaara, Jorma, Öfverstedt, Lars-Göran, Khoshnoodi, Jamshid, Zhang, Jingjing, Mäkelä, Eetu, Sandin, Sara, Ruotsalainen, Vesa, Cheng, R. Holland, Jalanko, Hannu, Skoglund, Ulf, Tryggvason, Karl
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15545998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI22562
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