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Nephrin Promotes Cell-Cell Adhesion through Homophilic Interactions

Nephrin is a type-1 transmembrane protein and a key component of the podocyte slit diaphragm, the ultimate glomerular plasma filter. Genetic and acquired diseases affecting expression or function of nephrin lead to severe proteinuria and distortion or absence of the slit diaphragm. Here, we showed b...

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Autores principales: Khoshnoodi, Jamshid, Sigmundsson, Kristmundur, Öfverstedt, Lars-Göran, Skoglund, Ulf, Öbrink, Björn, Wartiovaara, Jorma, Tryggvason, Karl
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892394/
https://ncbi.nlm.nih.gov/pubmed/14633607
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