Nephrin Promotes Cell-Cell Adhesion through Homophilic Interactions

Nephrin is a type-1 transmembrane protein and a key component of the podocyte slit diaphragm, the ultimate glomerular plasma filter. Genetic and acquired diseases affecting expression or function of nephrin lead to severe proteinuria and distortion or absence of the slit diaphragm. Here, we showed b...

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Main Authors: Khoshnoodi, Jamshid, Sigmundsson, Kristmundur, Öfverstedt, Lars-Göran, Skoglund, Ulf, Öbrink, Björn, Wartiovaara, Jorma, Tryggvason, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892394/
https://ncbi.nlm.nih.gov/pubmed/14633607
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