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Impact of Patient Ethnicity on the Metabolic and Immunologic Effects of PI3K-mTOR Pathway Inhibition in Patients with Solid Tumor Malignancies

PURPOSE: Inhibition of the phosphatidylinositol 3-kinase (PI3K)/mammalian target of Rapamycin (mTOR) pathway is associated with metabolic and immunologic perturbations that impact drug tolerability. Here, we studied whether PI3 kinase/mTOR pathway inhibitors are associated with greater metabolic imp...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Chemother Pharmacol
मुख्य लेखकों: Aggarwal, Rahul, Grabowsky, Jennifer, Strait, Noah, Cockerill, Alyson, Munster, Pamela
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5257275/
https://ncbi.nlm.nih.gov/pubmed/24934865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2510-0
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