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Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies

A complex interplay of intracellular signaling networks orchestrates normal cell growth and survival, including translation, transcription, proliferation, and cell cycle progression. Dysregulation of such signals occurs commonly in many malignancies, thereby giving the cancer cell a survival advanta...

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Detalhes bibliográficos
Main Authors: Tasian, Sarah K., Teachey, David T., Rheingold, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032892/
https://ncbi.nlm.nih.gov/pubmed/24904824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00108
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