Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies

A complex interplay of intracellular signaling networks orchestrates normal cell growth and survival, including translation, transcription, proliferation, and cell cycle progression. Dysregulation of such signals occurs commonly in many malignancies, thereby giving the cancer cell a survival advanta...

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Bibliographic Details
Main Authors: Tasian, Sarah K., Teachey, David T., Rheingold, Susan R.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032892/
https://ncbi.nlm.nih.gov/pubmed/24904824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00108
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