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Targeting the PI3K/AKT/mTOR Signaling Axis in Children with Hematologic Malignancies
The phosphatidylinositiol 3-kinase (PI3K), AKT, mammalian target of rapamycin (mTOR) signaling pathway (PI3K/AKT/mTOR) is frequently dysregulated in disorders of cell growth and survival, including a number of pediatric hematologic malignancies. The pathway can be abnormally activated in childhood a...
Uloženo v:
| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4214862/ https://ncbi.nlm.nih.gov/pubmed/22845486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11594740-000000000-00000 |
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