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Targeting the PI3K/AKT/mTOR Signaling Axis in Children with Hematologic Malignancies
The phosphatidylinositiol 3-kinase (PI3K), AKT, mammalian target of rapamycin (mTOR) signaling pathway (PI3K/AKT/mTOR) is frequently dysregulated in disorders of cell growth and survival, including a number of pediatric hematologic malignancies. The pathway can be abnormally activated in childhood a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4214862/ https://ncbi.nlm.nih.gov/pubmed/22845486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11594740-000000000-00000 |
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