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Impact of Patient Ethnicity on the Metabolic and Immunologic Effects of PI3K-mTOR Pathway Inhibition in Patients with Solid Tumor Malignancies
PURPOSE: Inhibition of the phosphatidylinositol 3-kinase (PI3K)/mammalian target of Rapamycin (mTOR) pathway is associated with metabolic and immunologic perturbations that impact drug tolerability. Here, we studied whether PI3 kinase/mTOR pathway inhibitors are associated with greater metabolic imp...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5257275/ https://ncbi.nlm.nih.gov/pubmed/24934865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2510-0 |
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