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Analysis of Mupirocin Resistance and Fitness in Staphylococcus aureus by Molecular Genetic and Structural Modeling Techniques

Chromosomal resistance to mupirocin in clinical isolates of Staphylococcus aureus arises from V(588)F or V(631)F mutations in isoleucyl-tRNA synthetase (IRS). Whether these are the only IRS mutations that confer mupirocin resistance or simply those that survive in the clinic is unknown. Mupirocin-re...

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Sonraí Bibleagrafaíochta
Main Authors: Hurdle, Julian Gregston, O'Neill, Alexander John, Ingham, Eileen, Fishwick, Colin, Chopra, Ian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC525403/
https://ncbi.nlm.nih.gov/pubmed/15504866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4366-4376.2004
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