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Analysis of Mupirocin Resistance and Fitness in Staphylococcus aureus by Molecular Genetic and Structural Modeling Techniques

Chromosomal resistance to mupirocin in clinical isolates of Staphylococcus aureus arises from V(588)F or V(631)F mutations in isoleucyl-tRNA synthetase (IRS). Whether these are the only IRS mutations that confer mupirocin resistance or simply those that survive in the clinic is unknown. Mupirocin-re...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Hurdle, Julian Gregston, O'Neill, Alexander John, Ingham, Eileen, Fishwick, Colin, Chopra, Ian
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525403/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15504866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.11.4366-4376.2004
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