Molecular Genetic and Structural Modeling Studies of Staphylococcus aureus RNA Polymerase and the Fitness of Rifampin Resistance Genotypes in Relation to Clinical Prevalence

The adaptive and further evolutionary responses of Staphylococcus aureus to selection pressure with the antibiotic rifampin have not been explored in detail. We now present a detailed analysis of these systems. The use of rifampin for the chemotherapy of infections caused by S. aureus has resulted i...

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Bibliographic Details
Main Authors: O'Neill, A. J., Huovinen, T., Fishwick, C. W. G., Chopra, I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346782/
https://ncbi.nlm.nih.gov/pubmed/16377701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.298-309.2006
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