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Delayed Development of Linezolid Resistance in Staphylococcus aureus following Exposure to Low Levels of Antimicrobial Agents

The development of resistance to linezolid (LZD) in gram-positive bacteria depends on the mutation of a single 23S rRNA gene, followed by homologous recombination and gene conversion of the other alleles. We sought to inhibit this process in Staphylococcus aureus using a range of antibacterial agent...

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Bibliografiske detaljer
Main Authors: Miller, Keith, O'Neill, Alexander J., Wilcox, Mark H., Ingham, Eileen, Chopra, Ian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415777/
https://ncbi.nlm.nih.gov/pubmed/18378719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01302-07
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