Chemical Diversity of Polyene Macrolides Produced by Streptomyces noursei ATCC 11455 and Recombinant Strain ERD44 with Genetically Altered Polyketide Synthase NysC

The gram-positive bacterium Streptomyces noursei ATCC 11455 produces a complex mixture of polyene macrolides generally termed nystatins. Although the structures for nystatins A(1) and A(3) have been reported, the identities of other components of the nystatin complex remain obscure. Analyses of the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bruheim, Per, Borgos, Sven E.F., Tsan, Pascale, Sletta, Håvard, Ellingsen, Trond E., Lancelin, Jean-Marc, Zotchev, Sergey B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15504830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.11.4120-4129.2004
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