Nystatin Biosynthesis and Transport: nysH and nysG Genes Encoding a Putative ABC Transporter System in Streptomyces noursei ATCC 11455 Are Required for Efficient Conversion of 10-Deoxynystatin to Nystatin

The genes nysH and nysG, encoding putative ABC-type transporter proteins, are located at the flank of the nystatin biosynthetic gene cluster in Streptomyces noursei ATCC 11455. To assess the possible roles of these genes in nystatin biosynthesis, they were inactivated by gene replacements leading to...

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Main Authors: Sletta, Håvard, Borgos, Sven E. F., Bruheim, Per, Sekurova, Olga N., Grasdalen, Hans, Aune, Randi, Ellingsen, Trond E., Zotchev, Sergey B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Chemistry; Biosynthesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280151/
https://ncbi.nlm.nih.gov/pubmed/16251298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4576-4583.2005
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