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Canonical DNA repair pathways influence R-loop driven genome instability
DNA repair defects create cancer predisposition in humans by fostering a higher rate of mutations. While DNA repair is quite well characterized, recent studies have identified previously unrecognized relationships between DNA repair and R-loop-mediated genome instability. R-loops are three stranded...
Enregistré dans:
| Publié dans: | J Mol Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5253333/ https://ncbi.nlm.nih.gov/pubmed/27452366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.07.014 |
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