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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
Genome instability via RNA:DNA hybrid-mediated R loops has been observed in mutants involved in various aspects of transcription and RNA processing. The prevalence of this mechanism among essential chromosome instability (CIN) genes remains unclear. In a secondary screen for increased Rad52 foci in...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3273840/ https://ncbi.nlm.nih.gov/pubmed/22279048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179721.111 |
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