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Mechanisms of genome instability induced by RNA processing defects

The role of normal transcription and RNA processing in maintaining genome integrity is becoming increasingly appreciated in organisms ranging from bacteria to humans. Several mutations in RNA biogenesis factors have been implicated in human cancers, but the mechanisms and potential connections to tu...

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Detalhes bibliográficos
Main Authors: Chan, Yujia A., Hieter, Philip, Stirling, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039741/
https://ncbi.nlm.nih.gov/pubmed/24794811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2014.03.005
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