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Mechanisms of genome instability induced by RNA processing defects

The role of normal transcription and RNA processing in maintaining genome integrity is becoming increasingly appreciated in organisms ranging from bacteria to humans. Several mutations in RNA biogenesis factors have been implicated in human cancers, but the mechanisms and potential connections to tu...

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Библиографические подробности
Главные авторы: Chan, Yujia A., Hieter, Philip, Stirling, Peter C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039741/
https://ncbi.nlm.nih.gov/pubmed/24794811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2014.03.005
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