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MET/HGF pathway activation as a paradigm of resistance to targeted therapies

Resistance to targeted therapeutics is a key issue limiting the long-term utility of these medications in the management of molecularly selected subsets of cancer patients, including patients with non-small cell lung cancer harboring oncogenic alterations affecting EGFR, ALK and other genes. Bypass...

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Bibliografiske detaljer
Udgivet i:Ann Transl Med
Main Authors: Ko, Brian, He, Tianfang, Gadgeel, Shirish, Halmos, Balazs
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253284/
https://ncbi.nlm.nih.gov/pubmed/28164089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.12.09
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